Best Things in Florence: In 48 hours, you can soak up the magic of this Renaissance city—but only if you have a plan. Florence is compact and easy to explore on foot, offering world-class museums, iconic landmarks, and unforgettable cuisine. But with millions of visitors crowding its streets, it’s easy to feel overwhelmed. Make the most of your time with this 48-hour itinerary for the BEST things in Florence!
48 Hours in Florence: Best things to do for food, art, and unforgettable sights.
Florence’s treasures are in high demand. But if you want to enjoy the best of the city in just 48 hours, you’ll need to make a few key bookings in advance. This itinerary includes the tours I booked (and loved), along with the ideal timing.
How to Get to Florence
By Air
If you fly into Florence, take the T2 Tram to get to the historic center. From Arrivals, simply walk five minutes to the tram stop, Aeroporto.
In approximately twenty minutes, get off at Alamanni-Stazione. Florence’s main train station, Santa Maria Novella, is across the street, and it’s about a 5-10 minute walk into the historic district.
By Train
From Rome, you can take the high-speed train, Trenitalia Frecciarossa, from Roma Termini. It takes about an hour and a half to arrive in Florence.
Arrive at Roma Termini about 20 minutes early. You’ll be travelling to Firenze Santa Maria Novella, but your train may continue on, so you might not see Florence (Firenze) on the screen. The board shows the final destination.
Know your train number and departure time to help you find your track.
Trains have limited space for luggage. I learned this the hard way, so try to travel light, as you may need to store your suitcase in the overhead compartment. If you want more details on train travel in Italy, check out this post.
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Where to Stay
Florence is super walkable. I love these kinds of cities where you can get almost anywhere on foot. Make the historic district your home base.
My top hotel pick is Bob W Ponte Vecchio. It’s located on the other side of the Arno, the Oltrarno. It’s super central, a 5-minute walk across Ponte Vecchio to the Uffizi.
Bob W focuses on short-stay apartments. I love their cozy rooms and amenities. I’ve stayed at Bob W in other cities and am always excited that their rooms come with a yoga mat.
Bob W doesn’t have a reception; everything is contactless. Door codes and stay information are sent via email or WhatsApp. Despite this, I felt very welcomed. Bob W messaged me to ensure that I got into my room and readily responded to any questions.
Typically, I only highlight accommodations where I have actually stayed. The Residenza d’Epoca Palazzo Riblet was at the top of my list when I returned to Florence. But unfortunately, this guesthouse has only three rooms, and all of them were sold out.
This is, however, where I’ll stay on my next visit and wanted to share this charming gem. Love its central location and frescoed ceilings.
Consider Staying at a Monestary
Looking for an affordable option? I highly recommend a Monastery Stay.
I’ve stayed in monasteries in both Rome and Florence. Found that the locations were central and close to major attractions. The rooms were clean, simple and had their own bathroom.
In Florence, I stayed in a former palazzo with a rose garden, antiques in the public areas, and a great breakfast.
There was also a curfew. Yep! This wasn’t an issue for me, but I thought you should know. Check out my blog post providing all the details and how to book.
Important Tips to Plan Your Trip
- This 48 Hour Itinerary is fast-paced.
- You’ll see Florence’s major highlights, but if you prefer a slower pace, with a few more gelato stops, spread it out over three days.
- The Uffizi Gallery and Galleria dell’Accademia are closed on Monday.
- Hotel prices increase on weekends, along with the number of tourists.
- Book your tours and accommodations well in advance! I cannot stress this enough!!
- I booked all of my tours and reservations two months in advance.
- If plans change, Get Your Guide and Viator typically allow you to cancel without charge or penalty 24 hours in advance. Similar for Hotels.com and Booking.com.
DAY 1: Best Things in Florence
9:00 AM – Breakfast
Your hotel (or monastery) may include breakfast. But highly recommend visiting one of Florence’s historic cafes.
I loved Caffè Gilli, which opened in 1733, and Caffè Concerto Paszkowski (1846).
Their interiors are beautiful, with old-world charm, polished wood, mirrors, ornate ceilings, and chandeliers. Step back in time as you start your day with a cappuccino and cornetto.
Insider Tip to Order Coffee in a Caffè in Italy:
Check out what you want to order. I am a huge fan of the cioccolato cornetto. Then go to the cashier to pay and place your order. Take your receipt over to the bar to pick up your coffee and pastry.
10:00 AM Florence Walking Tour
One of the easiest ways to see all of the BEST things in Florence is to take a walking tour.
Typically, this is the first thing I do when I visit a new city. It helps me understand the lay of the land while learning a little local history, plus I get some insider tips!
Recommend any one of these tours: Free Walking Tour, Renaissance and Medici Tales Walking Tour and Florence Highlights.
Noon Lunch – Mercanto Centrale
Whether you’re travelling solo or with a group, the perfect lunch spot to make everyone happy is at Mercanto Centrale.
The ground floor is a traditional market, and the second floor is a food hall where you can get pretty much anything, from local specialties to pizza, pasta, and even international dishes.
Order and pay at your preferred food stall, then find a table. If you’re with a group, you can each order at a different place and still sit all together. It’s a fun and tasty spot.
1:30 PM – Basilica San Lorenzo
Basilica San Lorenzo is a hidden gem. It doesn’t look like much on the outside. In fact, the marble facade that Michelangelo designed was never completed, as the Medici ran out of influence and money.
The most incredible part is the interior, which will trick your eyes as the colours, diminishing columns and repeating arches make the chapel appear far larger than it actually is.
Oh, and fun fact, Michelangelo had a secret room here! His sketches cover the walls, but unfortunately, it’s not currently open to the public.
2:15 PM – Duomo Complex Tour & Climb
The Duomo Complex Tour provides access to the Cathedral, Dome Climb, Baptistry, Bell Tower and Museum.
It starts with a guided tour of the area, and then you’re taken to the entrance to climb the Duomo’s massive cupola.
The views from the top are brilliant, but with my mild fear of heights, I didn’t stay out there for long. Found the climb up super interesting. You get up close to the frescoes on the dome’s interior. And you can admire Filippo Brunelleschi’s brilliance as you climb up through his ingenious double dome.
Note: The climb was never intended for tourists, but for workers, so the space is a little tight in spots
Upon exit, you’ll take a short walk through the Santa Maria del Fiore Cathedral. Make sure you take a look.
I personally find the interior underwhelming. Think all of the money and effort went into its spectacular exterior.
While your Duomo Complex ticket includes entrance into the cathedral, take a quick peek and decide if you really want to wait in the long line to get back inside.
4:15 PM – Gelato Break
As I was climbing the 463 stairs up the Duomo, the only thing keeping me going was thoughts of gelato.
Post climb, I walked two minutes to Badiani Gelato Tosinghi. Try their recreation of the original gelato flavour called Buontalenti, invented in 1565. Oh my! It’s rich, custardy and creamy. I’ve gone back more than once!
After a full day of exploring the best things in Florence, take a mini break before you head out for the evening.
6:15 PM – Photograph Ponte Vecchio
Ponte Vecchio is a medieval bridge across the Arno River. It’s the oldest bridge in the city, having survived floods and wars. Today, it is lined with shops, mainly selling jewellery.
Afternoon and early evening are the best times to take a photo. Head to the nearby Ponte Santa Trinta. From this bridge, you can gaze down at Ponte Vecchio. When the Arno River is still, you might even get a terrific reflection shot.
7:00 PM Sunset Food & Wine Tour
Hands down, this Food and Wine Tour was the highlight of my time in Florence. If you’re even thinking about booking a food tour — especially if you’re travelling solo — do it! There’s something magical about sharing good food and wine with strangers who quickly start to feel like friends.
The evening kicks off in the charming Piazza Santo Spirito (arrive early and pop into the beautiful old church at the end of the square — it’s been standing there for centuries). From the very first sip of prosecco, the vibe is set: relaxed, fun, and delicious.
You’ll stroll through the Oltrarno, one of Florence’s more authentic, less touristy neighbourhoods, stopping at hidden gems and local artisan spots that you’d probably miss on your own. There’s a lot of food, so come hungry — this is definitely dinner. And a highlight? You get to visit one of Florence’s legendary wine windows, which is just as cool (and historic) as it sounds.
Tip: Let your guide know in advance if you have dietary restrictions or preferences. They’re super accommodating.
DAY 2: Best Things in Florence
7:00- Breakfast
Consider Caffè Scudieri, which opens early if your hotel doesn’t include breakfast. Located on Piazza San Giovanni, this historic cafe is just steps from the Duomo.
You can sit outside while you sip your coffee, and oh, what a view! I can attest that the pastries are excellent.
8:00 AM – Uffizi Gallery Tour
It’s estimated that over 8,000 people visit the Uffizi Gallery daily. Is it worth braving the crowds? Absolutely!
You’ll see masterpieces like Botticelli’s Birth of Venus. Even if you’re not super into art, you’ll likely recognize Venus with her flowing golden hair, standing on a seashell.
And while you’ll never be able to dodge the crowds completely, you’re visit will be far more enjoyable if you book this early access, skip-the-line tour in advance. Your guide will whisk you past the line-ups outside and ensure that you see works of art by Leonardo da Vinci, Raphael, Caravaggio and Botticelli.
On my last two visits to Florence, the Vasari Corridor was still under renovation. But when I go again, I will definitely take this tour! It includes a walk through the corridor. Book the 8:15 am time slot.
The Vasari Corridor is a kilometre-long passage that was built for the Medici, an elevated walkway that weaves through buildings, a church and above shops. It allowed Florence’s ruling family to move from their offices to their palace safely.
10:30 AM – Wander the Uffizi on your Own
Don’t leave the Uffizi when your tour is over! One of the best things that I did in Florence was wander the Uffizi on my own.
Most of the masterpieces are on the second floor, so I went back for a second look at Botticelli’s ethereal Primavera. I was also mesmerized by Caravaggio’s Medusa — that terrifying face is said to be a self-portrait. But my favourite was the light-filled hallway, lined with statues, portraits and huge windows.
And don’t skip the first floor. It may be quieter and less famous, but when I visited, it was nearly empty — the perfect place to slow down and take it all in.
11:30 AM – Cafeteria at the Uffizi Gallery
A little pricey, but go for the view. The cafeteria is a hidden gem at the end of the second-floor gallery. Refuel while you take in close-up views of Palazzo Vecchio and Piazza della Signoria.
On your way out, you might want to browse for a few minutes in the gift shop—they kind of force you through it on your way to the exit. I was amazed by the number of art books, so if you’re feeling inspired after your visit, this might be the perfect place to pick up a few souvenirs.
12:30 PM – Stroll Through Piazza della Signoria
The fortress-like Palazzo Vecchio dominates this 13th-century public square. There’s a bronze statue of Cosimo I de’ Medici on a horse. As well as the fountain of Neptune. Apparently, the sea god’s face was modelled after Cosimo I de’ Medici. At the time, the locals made fun of this statue.
And how could it compete with Michelangelo’s brilliant statue of David? The original masterpiece stood in front of Palazzo Vecchio for 370 years. You can still see the replica, but the original was moved into the Galleria dell’Accademia.
Make sure to stroll by and admire the statues in the Loggia dei Lanzi. It is often the meeting point for guided tours of the Uffizi.
This open-air gallery is filled with statues. Probably the most famous and slightly gruesome is the bronze statue of Perseus holding up the head of Medusa.
1:00 PM – Arnolfo Tower Climb
My favourite viewpoint in Florence is from the Arnolfo Tower. I loved how you got so many different perspectives of the city, the surrounding hills, and it’s a great vantage point to take in the Duomo.
It’s 223 steps, but it didn’t feel like a burden, and the view was constantly changing as you climb. And if you are afraid of heights, this is a good climb as you are never really close to the edge.
Entrance into the tower is timed, so buy your ticket in advance so you can select the time slot you want. When I visited, I got the combo ticket that included time exploring Palazzo Vecchio with an audioguide and the Arnolfo Tower Climb. Don’t get me wrong, it was interesting seeing the inside of the former residence of the Medici. But for me, not a total wow. Would instead recommend purchasing just the tower climb ticket.
Don’t miss lingering a little in the first courtyard of Palazzo Vecchio, called Cortile di Michelozzo. It’s free to visit and quite impressive. It features carved columns, a fountain in the center and grotesque-style frescoes, which I found both fascinating and a little eerie.
2:15 PM – Affogato Break
I would fly to Florence just to have an Affogato at Violia Gelateria. It’s seriously that good! The same family has been running this gelateria since 1930.
I’ve had their gelato on its own (and yes, it’s incredible), but the affogato is divine. Served in a china cup with creamy gelato, and a shot of rich, hot espresso poured into the center. The contrast — hot and cold, sweet and bitter, and so creamy — it’s absolute perfection. My mouth is watering just thinking about it. Trust me: you need an affogato break here.
2:45 PM – Museo dell’Opera del Duomo – 1 hour to 3:45 PM
One of my favourite surprises was discovering the Museo dell’Opera del Duomo—a hidden gem and easily one of the best things Florence has to offer for art and history lovers. Entrance is included when you purchase the Duomo Complex Ticket.
The building once served as a workshop where it’s believed that Michelangelo sculpted his David. Today, it houses many of the original sculptures and artifacts from the Duomo, which have been replaced on the façade with replicas to protect them from the elements. You can also see the original bronze panels from the Baptistery doors, famously known as the Gates of Paradise.
Two unmissable highlights are the wooden model of Brunelleschi’s dome and the Terrazza del Brunelleschi.
Brunelleschi’s dome remains one of the most brilliant feats of Renaissance engineering, and the detailed model offers fascinating insight.
The terrace was my personal favourite. I was completely alone up there with just a security guard—and the incredible close-up view of the dome of Santa Maria del Fiore.
4:00 PM – L’Accademia – David – 75 Minutes to 5:15 pm
Visiting Michelangelo’s David at the Galleria dell’Accademia is undeniably one of the best things Florence has to offer.
Towering at over 17 feet, this marble masterpiece captures the physical perfection of the human body. I was mesmerized by David’s hands and lifelike veins. I couldn’t stop staring at them, wondering how the marble could look so much like soft flesh.
To truly appreciate David and the incredible art within the Accademia, take a guided tour. And try to book a later time slot, just before closing, so that the space is less crowded. Not only did the guide help us skip the confusing lines, but they also provided fascinating context. I probably would have missed Michelangelo’s Prisoners, a series of unfinished sculptures.
These figures are partially carved from marble blocks, and the Prisoners appear to be struggling to free themselves from the stone. It is quite remarkable to see these works in progress.
Walk to Piazzele Michelangelo
Walk up to Piazzele Michelangelo for the sunset and stunning views. It is an uphill climb, but it should be doable for most in about half an hour.
You can check here for sunset times. But expect a crowd, the views are spectacular, and everyone knows it! You can also see your third David of the day. There’s a large bronze replica at the viewing point.
For many, watching the sunset over Florence is one of the best things to do in Florence. I did not regret the climb and loved the view, but I did find the crowd a little overwhelming.
8:00 PM Florence’s Oldest Restaurant
End your time in Florence with dinner at Antico Ristorante Paoli—Florence’s oldest and, in my opinion, most beautiful restaurant. The frescoes on the walls of this nearly 200-year-old restaurant feel like you are dining in a museum.
Excellent service, a great wine list and a tempting menu, including iconic Florentian dishes like Bistecca alla Fiorentina. Make sure you book your table in advance. You can do an online reservation on their website.
Florence Best Things BONUS
Have tried my best to fit in all of my favourites into 48 hours, but missed a few things that are worth mentioning.
Oldest Pharmacy in the World
Officina Profumo-Farmaceutica di Santa Maria Novella, established in 1221 by Dominican friars, was officially commercialized in 1612 and has been selling perfumes, skincare, and herbal remedies ever since. It’s free to visit and stunningly beautiful.
Basilica Filled with Famous People
The Basilica of Santa Croce was built in the 13th century, with a stunning Neo-Gothic façade added in the 19th century. It is also the final resting place of iconic figures, like Michelangelo, Galileo, Machiavelli, and Puccini.
How to Return to Florence
Find Il Porcellino, a bronze wild boar statue at Mercato Nuovo. Rub his snout and drop a coin into the grate below—this guarantees your return to the city! It worked for me!
If you are planning a trip to Florence, please check out these posts: What to Eat in Florence and 5 Best Viewpoints in Florence.
